Manuscript Composition

Manuscripts must be written in English. The entire text should be double-spaced, including references. Submitting an incomplete manuscript or a manuscript that does not adhere to the word limits will cause a delay in review. Manuscripts must include the following sections in the order listed:


  • Title Page (including title, running title, author names and affiliations, and name of the corresponding author with complete contact information)

  • Abstract (including keywords)

  • Main Text (including Introduction, Materials and Methods, Results, Discussion, Conclusion, and Acknowledgements)

  • References

  • Legends

  • Tables

Title page

All submissions must contain a title page however brief the article may be (including, but not limited to, brief items such as editorials). The title page must contain the full title of the article; author(s) name(s); all departments and institutions in which the work was done; a running title with less than 40 characters; and the corresponding author's name, e-mail, and physical address for correspondence. Only one author may be designated as the corresponding author.


The acknowledgements section is where you may wish to thank people indirectly involved with the research (e.g., technical assistance; gifts of samples, reagents, or cell lines; loans of equipment or laboratory space; comments or suggestions during the creation of the manuscript). However, it is important that anyone listed here know in advance of your acknowledgement of their contribution, as documented during the submission process.Grants supporting this study also can be included in this section.Do not include dedications (e.g., to persons living or deceased).Dedications of articles are not permitted.



Center Liu1, 2, Medicine Chen1, Happy Wang1, 2,*

1School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan

2Department of Otolaryngology, Fu Jen Catholic University Hospital, New Taipei City, Taiwan

*Corresponding author: Happy Wang

School of Medicine, College of Medicine, Fu Jen Catholic University, 510 Zhongzheng Road, Xinzhuang Dist., New Taipei City, Taiwan

Tel & Fax: +886-2-29051234



Articles must carry a structured abstract of 250 words or less and up to 6 key words, with the following headings:

  • Background and purpose: Two or three sentences that describe a simple statement of the objectives, with no discursive material.

  • Methods: State the methods used to answer the study question. Include information on the study design, setting, subjects, interventions, outcome measures, and analyses, as appropriate.

  • Results: Give the central findings of your study, along with data and statistical details such as P values and confidence intervals, where appropriate. Be sure that  information in the abstract matches that in the main article.

  • Conclusion: State the meaning of your findings, being careful to address the study question directly and to confine your conclusions to aspects covered in the abstract. Give equal emphasis to positive and negative findings.

Abstracts for Case Reports, Brief Reports, and Review Articles are unstructured, but should include information on the background and purpose of the report, methods, results (or case report), and conclusion. Unstructured abstracts should be limited to 150 words.

Main text

The text includes the following sections: Introduction, Materials and Methods, Results, Discussion, and Conclusion. Subheadings in long papers are acceptable if needed for clarification and ease of reading. The Introduction should address the subject of the paper. The Methods section should identify the population, patient samples or animal specimens used, explain the laboratory utilized or study methods followed and state the statistical procedures employed in the research. The Results should include pertinent findings and necessary tables and figures. The Discussion should contain the conclusions based on the findings, a review of the relevant literature, a discussion of the application of the conclusions and implications for future research or medical applications. Following the Discussion, the Acknowledgments may be given. Those acknowledged should not include secretarial, clerical or technical staff whose participation was limited to the performance of their normal duties.


References should be indicated by superscripted numbers in consecutive order and in parentheses as they appear in the text and placed after punctuation. References should include the authors, title, journal name, year, volume number and inclusive page numbers. All references with more than three authors should list only three authors followed by the notation "et al." References to books should include authors, chapter title, names of editors, book title, city of publication, publisher, year of publication and inclusive page numbers. Volume and edition numbers should be included when appropriate. References in the text should be placed where relevant, be in consecutive Arabic numbers and set off in square brackets. In general, the number of references should not exceed 50. Verify references, including journal abbreviations, using MEDLINE. Examples of references are shown below.

Journal article

  • Feely J, Wilkinson GR, Wood AJJ. Reduction of liver blood flow and propranolol metabolism by cimetidine. New Engl J Med 1981; 304: 691-696.

  • Kaplan NM. Coronary heart disease risk factors and anti-hypertensive drug selection. J Cardiovasc Pharmacol 1982; 4 (Supple 2): 186-365.

  • Tada A, Hisada K, Suzuki T, et al. Volume measurement of intracranial hematoma by computed tomography. Neurol Surg (Tokyo) 1981; 9: 251-256. (In Japanese with English abstract).

Book chapter

  • Greenland S. Applications of stratified analysis methods. In: Rothman KJ, Greenland S, eds. Modern Epidemiology. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 1998: 288-300.

Entire book

  • MacMahon B, Pugh TF. Epidemiology: Principles and Methods. Boston: Little Brown and Co.; 1970.

Unpublished material, personal communications and unpublished papers, including papers submitted but not accepted yet, should be cited in the text, in parentheses. Include the name of the source or authors, date, and type of communication. For example:

  • AK Smith. How to establish a mice model for acute lung injury with mechanical stress? Written communication, 2003.

  • SB Jones. Renal nerves functioning as a renoprotectant. Unpublished data, 2003.


A legend must be included in the manuscript document after the reference list. Legends should include sufficient detail to be intelligible without reference to the text. Legends must define all symbols and include essential information. Rather than stating, "See text," legends should be more specific; for example, "See Results."

A legend is supplied for each illustration. Figures, models, and multimedia files should be numbered independently. The text of the article should refer to figures as "Figure 1," "Figure 2," etc., and multimedia files as "Movie 1," "Movie 2," etc.

These text citations of Figures, etc., must be in numerical order, in part to facilitate the placement of illustrations in their proper positions on the printed page.

Figure Format

Figures should be the smallest size that will convey essential scientific information and needs further confirmation Figures must be supplied at a minimum of 300 dpi.


All tables must be numbered according to consecutive order and a title. Each format of table should be double-spaced. Do not use color or shading, bold or italic fonts, or lines to highlight information. Indention of text and, sometimes, additional space between lines is preferred. Submitted tables should adhere to the following guidelines:

  1. Tables must not duplicate material in text or figures.

  2. Tables should be numbered consecutively with Arabic numerals and prepared with the size of the journal page in mind: 3.5 in. wide, single column, or 7 in. wide, double column.)

  3. Each table should have a brief title; explanatory notes should be in the legend, not in the title.

  4. Nonsignificant decimal places in tabular data should be omitted.

  5. Short or abbreviated column headers should be used and explained if necessary in the legend.

  6. Statistical measures of variations such as SD or SE must be identified. (Example: "Values are means ± SE.")

  7. able footnotes should be listed in the order of their appearance and identified by standard symbols: *, †, ‡, § for four or fewer; for five or more, consecutive superscripted lowercase letters should be used (e.g., a, b, c, etc.).